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A collaborative effort by Helmholtz Munich, the German Diabetes Center, and the German Center for Diabetes Research

Cardiac arrhythmia: When the heartbeat stumbles

Scientific support: Dr. Elric Zweck

In cardiac arrhythmias, the heart beats too quickly, too slowly, irregularly or a combination of these. They are widespread. If the heart is out of sync, this does not always have to be dramatic, but it can have life-threatening consequences.

There are many different factors that can promote the development of cardiac arrhythmias. In addition to certain substances such as caffeine or alcohol, lifestyle and illnesses such as severe overweight (obesity), high blood pressure and other heart diseases also play a role. Diabetes can also increase the risk.

Cardiac arrhythmias do not always cause symptoms. Whether they are harmless or potentially dangerous can only be determined by a detailed examination. Once the cause has been determined, the symptoms can be alleviated and possible consequences prevented.



1. What are cardiac arrhythmias?

A complex system in the body ensures that the heart muscle pumps blood through the blood vessels at a regular rhythm. At rest, this occurs at 60 to 90 beats per minute. This rhythm is controlled by electrical impulses. But sometimes the heart gets out of sync: It beats too fast, too slowly or irregularly. Experts then speak of what are called cardiac arrhythmias.

As there are many different forms of cardiac arrhythmia, they are classified according to several characteristics:

  • According to the place of their origin: In the atrium (supraventricular) or in one of the two ventricles (ventricular)
  • According to the heart rate: Accelerated heartbeat (tachycardia) or slowed heartbeat (bradycardia)
  • According to the mechanism of origin: Disturbed formation of electrical impulses or faulty transmission of the excitation (excitation disturbances)

 

Cardiac arrhythmias are widespread in Germany. The most common is the atrial fibrillation. Over-excitation of the atria results in the atria no longer being able to pump efficiently and thus fill the downstream ventricles with less blood. In addition, the overall heartbeat is often too fast. As a result, cardiac output decreases as the heart muscle pumps less blood.

Around 1.6 million people in Germany (around 2 percent of the population) are affected. Experts believe that twice as many people will suffer from atrial fibrillation in the next 50 years. There are several reasons. Among other things, the fact that more and more people are overweight and are getting older plays a role.

Certain forms of cardiac arrhythmia occur more frequently in men, while others occur predominantly in women. The widespread atrial fibrillation, for example, is more common in men. However, women feel more affected by the symptoms of atrial fibrillation in everyday life.

 

Cardiac arrhythmias are generally harmless, especially in young people and people without pre-existing conditions. This can be caused, for example, by stress, caffeine or alcohol consumption. However, some forms of cardiac arrhythmia may also be dangerous. Then the cause is usually another heart disease. In general, symptoms such as heart stumbling should be clarified by a cardiologist – especially if there is already a family history of heart problems.


2. What are the consequences of cardiac arrhythmia?

Many forms of cardiac arrhythmia are harmless – especially if there is no heart disease. However, if left untreated, certain forms of cardiac arrhythmia increase the risk of serious complications.

Atrial fibrillation is one of the most important risk factors for a stroke. Around 25 in 100 strokes caused by a blocked blood vessel are due to atrial fibrillation. The reason: The heart pumps less blood through the atria, so the blood coagulates more quickly and is more likely to form blood clots. These can enter the brain via the bloodstream, clog vessels there and lead to a stroke.

Much rarer, but highly dangerous, are malignant cardiac arrhythmias, which always represent an emergency and are typically accompanied by severe symptoms or even unconsciousness. This can be accompanied by the heart first beating over 300 times a minute (ventricular fibrillation) and then stopping beating (sudden cardiac death). This can occur, for example, in the event of a heart attack.


3. What increases the risk of cardiac arrhythmias?

The following risk factors can promote cardiac arrhythmias:

  • Heart diseases such as heart failure, coronary heart disease (CHD) and heart attack
  • Congenital heart defects such as malformations of the conduction system
  • Stimulants and drugs such as alcohol, caffeine, nicotine, cocaine or amphetamines
  • Electrolyte deficiency (especially potassium and magnesium)
  • Lifestyle factors such as obesity, elevated blood lipid levels or lack of exercise
  • Age: Older people are more frequently affected by diseases that promote cardiac arrhythmias
  • Drugs such as certain heart medications or antidepressants
  • Mental illnesses such as depression
  • Other diseases such as diabetes, sleep apnea (breathing disorders during sleep), chronic kidney disease, vascular disease, high blood pressure, hyperthyroidism or chronic obstructive pulmonary disease (COPD)
  • High emotional stress such as stress, anxiety, anger and the like

4. How can cardiac arrhythmias be prevented?

You can prevent cardiac arrhythmias by trying to reduce or avoid possible risk factors. If you are sensitive to stimulants with caffeine such as coffee or energy drinks, it is best to avoid them. A balanced electrolyte balance is also important for normal heart function. An electrolyte deficiency can occur due to heavy sweating, diarrhea or the intake of dehydrating medication. In these cases, make sure you drink enough, for example mineral water or unsweetened tea, and eat plenty of fruit and vegetables.

You should also reduce the risk of cardiovascular diseases. To achieve this:

 

If you already have cardiovascular diseases such as high blood pressure, you should get medical treatment, particularly in order to prevent atrial fibrillation.


5. How are cardiac arrhythmia, diabetes and obesity related?

Elevated blood sugar levels permanently damage the heart and blood vessels. As a result, people with diabetes are more often affected by cardiovascular diseases such as heart failure, heart attack or coronary heart disease (CHD) than people without diabetes. These heart diseases in turn increase the risk of cardiac arrhythmia. People with diabetes suffer more frequently from atrial fibrillation. People with diabetes are more likely to have structural changes in their atria which then store more connective tissue, resulting in an increased risk of atrial fibrillation.

However, it is not only diabetes itself that can play a role in the development of cardiac arrhythmias: Type 2 diabetes is often accompanied by high blood pressure, increased age and severe overweight (obesity) – all of these are factors that can promote atrial fibrillation independently of diabetes.

Good to know:

Obesity is an important influencing factor for what is called the sleep apnea syndrome, i.e., breathing disorders during sleep. Sleep apnea is in turn an important risk factor for atrial fibrillation.

The risk of atrial fibrillation is particularly high when elevated blood sugar levels are accompanied by high blood pressure, obesity and a disturbed fat metabolism. This combination of risk factors is also known as metabolic syndrome. Severely overweight (obese) people in particular are at risk of developing metabolic syndrome.

In addition, people with diabetes are more likely not to notice heart problems, as elevated blood sugar levels may also damage the nervous system and thus reduce sensitivity. However, unknown and untreated heart diseases may lead to life-threatening cardiac arrhythmias such as ventricular fibrillation. It is therefore important for people with diabetes to have regular check-ups for cardiovascular diseases. A healthy lifestyle can further reduce the risk of complications.


6. What are the symptoms of cardiac arrhythmia?

Cardiac arrhythmias can trigger many different symptoms. Typical symptoms include pauses, heart stumbling, palpitations, or a fluttering feeling in the chest or throat. Whether there is a serious cause behind the cardiac arrhythmia can only be clarified by a medical examination including an electrocardiogram (ECG).

Important warning signs are, for example:

  • Heart pounding or palpitations
  • Dizziness or drowsiness
  • Tiredness or weakness
  • (Near) faints
  • Shortness of breath and anxiety
  • Pain or pressure in the chest
  • Alternating fast and slow heartbeat
  • Sweating

Good to know:

Cardiac arrhythmias sometimes show signs that are similar to those of a heart attack. In the event of a heart attack, the symptoms often occur suddenly and last longer than 5 minutes. Find an overview of the symptoms of a heart attack here.

If a heart attack is suspected, immediate action is required. Call the emergency services immediately (112 in Germany).

Some people with cardiac arrhythmia have few or no symptoms. Atrial fibrillation, for example, often causes no symptoms and therefore usually remains undetected for a long time. Long undetected or untreated atrial fibrillation can cause heart failure, which can lead to reduced performance, shortness of breath or death in affected persons. This tends to occur slightly more frequently in men than in women. On average, affected women experience certain symptoms – especially palpitations and feelings of anxiety – more intensely than men.


7. How are cardiac arrhythmias diagnosed?

To diagnose cardiac arrhythmia, doctors first ask about the symptoms and the situations in which they occur, as well as any previous illnesses and heart diseases in the family. This is followed by further examinations.

Electrocardiogram

An electrocardiogram (ECG) shows whether the heart is beating normally or whether there are any irregularities. Since cardiac arrhythmias often only occur intermittently or under certain conditions, special ECG examinations are often necessary:

  • Long-term ECG: A small recording device measures the heart activity over 24 hours.
  • Event recorder: Records the heart currents over a longer period of time (several months). They can be worn as a bracelet, finger clip or plaster.
  • Exercise ECG: Shows how the heart reacts to physical exertion.
  • Smartwatches: Can support the diagnosis of cardiac arrhythmias. However, they are not yet a medical standard.

Ultrasound examination (echocardiography)

With the help of an ultrasound examination, the size, structure and movement of the heart muscle can be visualized and possible changes or diseases be detected. Sometimes doctors insert the transducer via the esophagus, which lies behind the heart. The images from a transthoracic echocardiogram (TTE or colloquially “swallowing echo”) provide particularly detailed images.

Further examinations

Further examinations may be necessary for a more precise diagnosis:

  • Cardiac catheterizations reveal circulatory disorders in the vessels. Electrophysiological cardiac catheterization (EPC), on the other hand, can show exactly where cardiac arrhythmias occur in the heart.
  • Blood tests, for example to clarify a thyroid disease.
  • Further imaging examinations such as magnetic resonance imaging (MRI) or computer tomography (CT) to obtain detailed images of the heart.

8. How are cardiac arrhythmias treated?

Your attending physicians will decide what to do in the event of cardiac arrhythmia and whether treatment is possible or necessary. This decision depends on the type of cardiac arrhythmia, the severity of the symptoms and whether there is an increased risk of complications.

Medication against cardiac arrhythmias

Various medications such as antiarrhythmic drugs or beta blockers can stabilize the heart rhythm so that cardiac arrhythmias either no longer occur at all or only in a milder form. People with atrial fibrillation are often given additional anticoagulants. These are intended to prevent a stroke.

Non-Drug treatment of cardiac arrhythmias

If treatment with drugs is not sufficient, further measures are used. In some cases, minor surgical interventions are necessary.

  • Electrical cardioversion: Electrodes attached to the chest send an electrical impulse to the heart. The heart stops the heart rhythm briefly and then starts again. In many cases, the heart then begins to beat at a normal rhythm again.
  • Catheter ablation: Doctors insert a fine tube into the heart. With the help of cold or high-frequency electrical waves, small areas of tissue in the heart that trigger the cardiac arrhythmia are destroyed through this tube.
  • Pacemaker: The pacemaker sends electrical impulses that put the heart back in a normal rhythm. If permanent application is necessary, the small devices are placed under the skin.
  • Implantable cardioverter defibrillator (ICD): In case of need, defibrillators can deliver an electric shock if a cardiac arrest is imminent. Most implantable defibrillators have a dual function and also serve as a pacemaker.

Did you Know?

There are exercises that can help with certain cardiac arrhythmias, especially with tachycardia, which is not caused by atrial fibrillation. These vagal maneuvers aim at stimulating the vagus nerve, which, besides controlling a number of things, leads to the heart and can downregulate the heart rate. For example, hold your nostrils closed and try to exhale forcefully through your nose (Valsalva maneuver). A quickly drunk glass of cold water or a cold, damp towel on the face has a similar effect. However, ask your medical treatment team in advance whether you should use these techniques!

For successful treatment, it is important to follow the treatment recommendations consistently. The earlier cardiac arrhythmias are recognized and treated, the better the prognosis. Targeted treatment can alleviate the symptoms and prevent undesirable consequences.

Sources:

Brugada, J. et al.: 2019 ESC Guidelines for the management of patients with supraventricular tachycardia. The Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC): Developed in collaboration with the Association for European Paediatric and Congenital Cardiology (AEPC). In: Eur Heart J, 2020, 41: 655-720
Desai, D. S. et al.: Arrhythmias. In: StatPearls Publishing. Stand: 06/2023 (Letzter Abruf: 07.05.2024)
Deutsche Herzstiftung: Deutscher Herzbericht. 2022 (Letzter Abruf: 07.05.2024)
Deutsche Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e.V. et al.: ESC Pocket Guidelines: Diagnose und Behandlung von Vorhofflimmern. Version 2020
Deutsche Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e.V. et al.: ESC Pocket Guidelines: Diabetes, Prädiabetes und kardiovaskuläre Erkrankungen. Version 2019
Ding, M. et al.: Time trends in atrial fibrillation-related stroke during 2001-2020 in Sweden: a nationwide, observational study. In: Lancet Reg Health Eur, 2023, 28: 100596
Fu, Y. et al.: Association between depression and risk of triggering ventricular arrhythmias: A meta-analysis. In: Int J Clin Pharmacol Ther, 2019, 57: 306-314
Glikson, M. et al.: 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: Developed by the Task Force on cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology (ESC) With the special contribution of the European Heart Rhythm Association (EHRA). In: Eur Heart J, 2021, 42: 3427-3520
Joglar, J. A. et al.: 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. In: Circulation, 2024, 149: e1-e156
Leopoulou, M. et al.: Diabetes mellitus and atrial fibrillation-from pathophysiology to treatment. In: World J Diabetes, 2023, 14: 512-527
Linde, C. et al.: Sex differences in cardiac arrhythmia: a consensus document of the European Heart Rhythm Association, endorsed by the Heart Rhythm Society and Asia Pacific Heart Rhythm Society. In: EP Europace, 2018, 20: 1565-1565ao
Lip, G. Y. H. et al.: Sex-related differences in presentation, treatment, and outcome of patients with atrial fibrillation in Europe: a report from the Euro Observational Research Programme Pilot survey on Atrial Fibrillation. In: EP Europace, 2015, 17: 24-31
Marx, N. et al. (Hrsg.) (2023): Klinische Kardiologie – Krankheiten des Herzens, des Kreislaufs und der herznahen Gefäße. 9. Auflage. Springer Verlag, Berlin/Heidelberg, ISBN: 978-3-662-62931-4
Nazarian, S. et al.: Diagnostic Accuracy of Smartwatches for the Detection of Cardiac Arrhythmia: Systematic Review and Meta-analysis. In: J Med Internet Res, 2021, 23: e28974
Nowak, B. et al.: Metabolisches Syndrom und Vorhofflimmern. In: Herzschr Elektrophys, 2022, 33: 367-372
Veltmann, C. et al.: Wearable-basierte Detektion von Arrhythmien. In: Kardiologe, 2021, 15: 341-353
As of: 07.05.2024