Show main content
A collaborative effort by Helmholtz Munich, the German Diabetes Center, and the German Center for Diabetes Research

Heart attack: The most important facts at a glance

Scientific support: Prof. Dr. Barbara Thorand, Dr. Margit Heier

In the event of a heart attack, the blood flow supplying the heart is usually completely or partially blocked by blood clots in the coronary arteries. As a result, the affected heart tissue is damaged. Important controllable risk factors for a heart attack are smoking, diabetes, high blood pressure, obesity, elevated blood lipid levels and psychological stress. A healthy lifestyle helps to reduce these risk factors.

After a heart attack, doctors try to restore blood flow to the blocked blood vessel as quickly as possible and keep the vessel permanently open.



1. What is a heart attack?

The task of the heart muscle is to pump blood through the body. A heart attack (myocardial infarction) occurs when the blood flow to the heart muscle is completely or partially blocked. This is usually triggered by a blood clot in the coronary arteries, i.e., in the blood vessels that supply the heart with blood. In this context, doctors also speak of acute coronary syndrome. This is an umbrella term for situations in which the blood supply to the heart muscle is suddenly no longer guaranteed.

In addition to heart attacks, this term also includes unstable angina pectoris, in which coronary arteries are narrowed and severely restrict blood flow. All blockages begin with the formation of what are called plaques (deposits) in the coronary arteries. The plaques consist mainly of fat, cholesterol, calcium and connective tissue. Over time, they can become larger and larger and constrict the arteries. Doctors refer to the process of plaque formation as arteriosclerosis.

If plaques in an artery rupture or break open, a blood clot can form. This can block the artery and reduce or stop the blood flow to the heart muscle. As a result, the heart muscle is insufficiently supplied with oxygen and nutrients. This is called ischemia. Without sufficient oxygen, the cells in the heart muscle die, which is characteristic of a heart attack. The body cannot replace the dead tissue.

 

In Germany, more than 300,000 people suffer a heart attack every year. Most heart attacks occur in men between the ages of 68 and 76, and in women between the ages of 76 and 84.


2. What are the consequences of a heart attack?

Every person with a heart attack has his or her own medical history. The consequences and prognosis, i.e., the probable course of the disease, depend on, but are not limited to:

  • how quickly the heart attack was treated by a doctor,
  • how severe the heart attack was,
  • how much tissue in the heart has been damaged,
  • which other underlying diseases are present,
  • how intensely affected people change their lifestyle after a heart attack.

 

Common consequences of a heart attack are fatigue, shortness of breath, weakness, but also anxiety, depression, or post-traumatic stress disorder (PTSD).


3. What increases the risk of a heart attack?

The most important controllable risk factors for a heart attack include:

  • Smoking
  • Elevated blood sugar levels (prediabetes or diabetes)
  • High blood pressure
  • Overweight or severe overweight (obesity), especially in the abdominal region
  • Elevated blood lipid levels (especially elevated LDL cholesterol)
  • Psychological stress
  • Lack of sleep

 

In the short term, a rich diet, severe mental stress, cold, drugs and many other factors also increase the risk of a heart attack.

 

Non-controllable risk factors for a heart attack are:

  • Age: The number of heart attacks gets higher with increasing age.
  • Gender: Men are more likely to suffer a heart attack at a younger and middle age than women.
  • Genetic predisposition: If close relatives (grandparents, parents) had a heart attack, the likelihood of also suffering a heart attack is greater.

Good to know:

Would you like to find out more about your risk of developing cardiovascular disease within the next 10 years? Click here for the Cardiovascular Disease Risk Score.


4. How can a heart attack be prevented?

You can significantly reduce the risk of a heart attack by adopting a healthy lifestyle. The following aspects help to prevent a heart attack:

  • Do not smoke: Smoking – including passive smoking – is a significant risk factor for cardiovascular disease. Your doctor’s practice or your pharmacy will help you to stop smoking. Ask for individual advice. Many health insurance companies also offer courses to help you stop smoking or subsidize participation in such courses – just ask.
  • Balanced diet: Eat a healthy and balanced diet with plenty of vegetables, pulses, fruit, wholegrain products and “healthy” fats. These are found, for example, in fish, nuts and vegetable oils such as rapeseed, olive or linseed. Take advantage of the colorful variety of foods.
  • Pay attention to fat and salt consumption: Reduce your consumption of saturated fatty acids, trans fats, cholesterol, and common salt. To achieve this, cook as much as possible yourself, avoid fast food and convenience products and season with herbs to reduce salt. The German Nutrition Society advises adults to consume a maximum of 6 grams of salt per day. This corresponds to about one teaspoon. Note: Ready-made products also contain salt.
  • More exercise: Regular exercise, at least 150 minutes of moderate endurance training per week, can also improve heart health. This includes activities such as walking, running, cycling or swimming. Incorporate more exercise into your daily routine, especially if you sit a lot.
  • Reach your normal weight: If you are overweight, try to reduce your body weight. A body mass index (BMI) of 18.5 to 24.9 kg/m² is considered normal weight. Values between 25.0 and 29.9 kg/m² are considered overweight. A BMI of over 30 kg/m² is considered severe overweight (obesity). This applies equally to men and women.
  • Reduce your waist circumference: Weight loss measures can also reduce your waist circumference. The standard values for Europe are a waist circumference of less than 80 centimeters for women and of less than 94 centimeters for men.
  • Stabilize your blood pressure: High blood pressure (hypertension) also increases the risk of cardiovascular disease. Anyone with high blood pressure should measure it regularly and take appropriate lifestyle measures to counteract it. This includes, for example, a healthy and balanced diet and regular exercise. If this is not enough, medication to control blood pressure (antihypertensives) can help. It is important to take them consistently and according to the doctor’s instructions.
  • Bear your blood sugar in mind: If you have diabetes, it is important to keep an eye on your blood sugar levels and take your prescribed medication as directed. Find more information on the individual forms of diabetes in our “Living with Diabetes” portal. Even people with prediabetes have an increased risk of cardiovascular disease. Appropriate lifestyle measures can help to normalize blood sugar levels.
  • Alcohol only in moderation: Avoid alcohol or try to reduce your alcohol consumption as much as possible. According to current scientific knowledge, even small amounts of alcohol may be harmful.
  • Avoid stress: Chronic stress may also increase the risk of heart attacks. Learn techniques for coping with stress, for example relaxation techniques (yoga, progressive muscle relaxation according to Jacobson) or meditation. Many health insurance companies cover the costs of such courses in full or at least in part.
  • Lower blood lipid levels: Have your blood lipid levels determined at your doctor’s practice. A low level of LDL cholesterol is good for heart health. If necessary, take medication as recommended by your doctor to lower and ideally normalize your blood lipid levels.
  • Healthy sleep: Sleep long enough, between 7 and 9 hours per night. Too much or too little sleep can be harmful. You can improve the quality of your sleep, for example, by being physically active during the day, always going to bed at similar times and banishing all electronic devices from the bedroom. The bedroom should also be dark and as quiet as possible.

5. How are heart attacks, diabetes and obesity related?

People with prediabetes and diabetes have an increased risk of cardiovascular disease and therefore also of heart attacks. In general, the risk of a heart attack in people with diabetes is about twice as high as in people without diabetes. However, the risk also depends on the duration of diabetes.

Studies indicate that people who already have type 1 diabetes before the age of 15 have a more than 9 times higher risk of developing a heart attack than people without type 1 diabetes. As regards type 2 diabetes, studies show: The earlier the disease occurs, the greater the risk of a heart attack. If the disease occurs before the age of 40 years, the risk increases by a factor of three, while the risk increases by a factor of almost 1.5 if the age of onset is higher (60 to 70 years).

In addition to the age at which the disease is first diagnosed, the risk of a heart attack also depends on whether people with diabetes already have other cardiovascular diseases (such as high blood pressure) and other risk factors. These include, for example, a lack of exercise, smoking or a high-fat diet. These factors further increase the risk of a heart attack.

 

Overweight or severe overweight (obesity) is also associated with an increased risk of developing a heart attack. The risk is particularly high if people who are overweight or obese also have metabolic syndrome. Metabolic syndrome refers to the joint occurrence of obesity, elevated blood lipid and fasting blood sugar levels as well as high blood pressure. A meta-analysis revealed a 72 percent increased risk of heart attack for people with obesity and metabolic syndrome. The analysis showed that obesity along with metabolic syndrome increased the risk of a heart attack by 58 percent.

But even if there is no metabolic disorder such as high blood pressure, type 2 diabetes or elevated blood lipid levels, obesity is associated with an increased risk of cardiovascular disease. Metabolically healthy women with obesity had a 39 percent higher risk of cardiovascular disease compared to metabolically healthy women of normal weight.


6. What are the symptoms of a heart attack?

Acute chest discomfort, which affected people describe as severe pain, pressure, tightness, heaviness or burning, are possible signs of a heart attack. The symptoms usually last longer than 5 minutes and can radiate to one or both arms, the jaw, the neck, the back or the abdomen.

Other symptoms of a heart attack are:

  • Shortness of breath and breathlessness
  • Fear of death
  • Dizziness
  • Drowsiness and weakness (even without pain)
  • Nausea
  • Feeling of sickness and vomiting
  • Sweating and perspiration
  • Pain in the upper abdomen
  • Tiredness or even depression

Good to know:

Not all symptoms necessarily occur with every heart attack. The symptoms of a second infarction (reinfarction) can also differ significantly from those of the first event.

These symptoms sometimes appear suddenly. Nevertheless, up to 50 percent of all affected people show warnings of a heart attack. These are more common in women than in men. They include fatigue, anxiety, sleep disorders, shortness of breath and slight pain in the chest or arms.

The symptoms of a heart attack in women are often less severe. Severe pain that radiates to other areas of the body does not always occur as it does in men. Women are more likely to experience a feeling of pressure or tightness.

Other prominent symptoms of a heart attack in women can include:

  • Shortness of breath
  • Sweating
  • Back pain
  • Nausea
  • Vomiting
  • Pain in the upper abdomen
  • Tiredness or even depression

Many people who have these symptoms think of other illnesses, for example of abdominal complaints, but not of a heart attack. This involves the risk of seeking medical help too late.

 

People with diabetes also often have different symptoms, which can lead to delayed diagnosis and treatment. There may be differences between people with and without diabetes:

  • Typical chest pain symptoms may be absent
  • Sweating, nausea, dizziness and fear of death are less common in people with diabetes than in people without diabetes
  • Shortness of breath is more common in people with diabetes than in people without diabetes

First aid in the event of a heart attack

Therefore: If you experience the symptoms described above, this is always a medical emergency, even if you think it’s not a heart attack. Do not hesitate and call the emergency services immediately (112 in Germany). Under no circumstances should you drive yourself to hospital or a doctor’s practice.

As a family member, you can take the following measures in the event of a heart attack until the emergency services arrive:

  • Do not leave the person alone. The risk of cardiac arrest is high.
  • Loosen tight clothing.
  • Open the windows to provide more fresh air.
  • Position the affected person with his or her upper body slightly elevated.

 

If the affected person does not respond when spoken to and the chest does not move with breathing, this indicates a cardiovascular arrest. First aid can save lives in such a situation.

 

Proceed as follows during cardiopulmonary resuscitation:

  1. Lay the affected person as flat as possible on the floor. A firm base is important!
  2. Check respiration:
    • Clear the person’s airways by tilting his or her head back and lifting his or her chin at the same time.
    • In this position, control the person’s breath by looking, hearing and feeling:
      • Check whether the chest rises and falls.
      • Place your ear over the affected person’s mouth and nose and listen for breathing noises.
      • Use your cheek to check whether you can feel a flow of air from the affected person.
      • Control the breath for a maximum of 10 seconds.
  3. Make an emergency call!
  4. If breathing cannot be safely felt, start resuscitation:
    • Place the balls of your hands in the center of the affected person’s chest above his or her sternum. Press the sternum at least 5 centimeters deep with a frequency of about 100 to 120 times per minute. This is the beat of the song “Stayin’ Alive” by the Bee Gees or “Poker Face” by Lady Gaga. Pressing on the sternum is known as compression.
    • Fully release the chest between compressions.

Continue chest compressions until professional help arrives or until the affected person is breathing normally again.

Good to know:

In the first few minutes after a cardiac arrest, mouth-to-mouth resuscitation is not necessary, as the oxygen reserves in the body are still sufficient for 7 to 8 minutes. It is crucial to get the blood flow going again immediately.

Don’t be afraid of mistakes! The worst mistake is not to act!

Regular refresher first aid courses take away the fear of taking action and can save lives. You can find offers for first aid courses on the website of the German Red Cross, the Malteser Hilfsdienst e.V. or the Johanniter (Websites in German), for example.

If there are more than one rescuer on site, you can take turns giving chest compressions and send someone out to find an automated external defibrillator, or AED for short. Such devices can often be found in public buildings, at train stations or in busy squares.

 

Proceed as follows when using an automated external defibrillator (AED):

  • Turn on the AED and follow the voice or visual instructions to apply the electrodes and deliver a shock if necessary. Do not worry: Unnecessary shocks are not triggered.
  • Only interrupt chest compressions if the AED prompts you to do so.

7. How is a heart attack diagnosed?

In order to recognize a heart attack, doctors register typical symptoms during a conversation if the affected person is conscious. They auscultate the heart and lungs, examine the blood for heart attack markers such as troponin (a protein) and heart activity using an electrocardiogram (ECG) and apply various imaging techniques such as ultrasound examinations.

A cardiac catheterization can be used to detect blocked blood vessels and additionally open the blocked blood vessels directly at the same time.

 

Doctors differentiate between what is called an ST elevation myocardial infarction (STEMI) and a non-ST elevation myocardial infarction (NSTEMI). The STEMI shows pronounced changes in the ECG. One of the larger coronary arteries is completely blocked. In case of an NSTEMI, a coronary artery is usually only partially or temporarily blocked.


8. How is a heart attack treated?

During emergency medical treatment, people with a suspected heart attack are given painkillers, oxygen and medication to prevent new blood clots and lower blood pressure if necessary.

In hospital, affected persons are examined and treated in specialized departments, which are called “chest pain units”, wherever possible. Based on the findings of the examinations, the attending physicians decide on the next steps.

 

The therapies include cardiac catheterization (percutaneous coronary intervention, or PCI for short): A catheter is inserted into the affected artery in order to widen the constriction with a small balloon. Doctors then place a stent (a tubular metal mesh) to keep the affected blood vessel permanently open.

In many cases, thrombolysis can be reasonable. Special medication is administered to dissolve the existing blood clot.

 

After acute treatment, people who have had a heart attack are given medication to prevent further blood clots, elevated blood pressure and/or increased blood lipid levels, depending on the results of the tests. The exact drug therapy is determined by the attending physician.

 

A heart attack is often followed by medical rehabilitation, or rehab for short. Important goals are:

  • The successful return to everyday life.
  • A healthy lifestyle and consistent use of prescribed medication to reduce the likelihood of further heart attacks.

Sources:

Byrne, R. A. et al.: 2023 ESC Guidelines for the management of acute coronary syndromes: Developed by the task force on the management of acute coronary syndromes of the European Society of Cardiology (ESC). In: Eur Heart J, 2023, 44: 3720-3826
Deutsche Adipositas-Gesellschaft et al.: Interdisziplinäre Leitlinie der Qualität S3 zur „Prävention und Therapie der Adipositas“. Version 2.0. 2014 (Gültigkeit abgelaufen, in Überarbeitung)
Deutsche Gesellschaft für Allgemeinmedizin und Familienmedizin e.V.: S3 Leitlinie Hausärztliche Risikoberatung zur kardiovaskulären Prävention. 2017 (Gültigkeit abgelaufen, in Überarbeitung)
Deutsche Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e.V.: Herzinfarkt-Patienten werden immer älter. (Letzter Abruf: 07.05.2024)
Deutsche Gesellschaft für Prävention und Rehabilitation von Herz-Kreislauferkrankungen e.V.: Pocket-Leitlinie zur Rehabilitation von Patienten mit Herz-Kreislauferkrankungen. 2008
Deutsche Hauptstelle für Suchtfragen e.V.: Empfehlungen zum Umgang mit Alkohol. 2023
Deutsche Herzstiftung e.V.: Koronare Herzkrankheit und Herzschwäche – was ist bei Frauen anders? Sonderdruck. 2022
Dhingra, R. et al.: Age as a Cardiovascular Risk Factor. In: Med Clin North Am, 2012, 96: 87-91
Eckel, N. et al: Transition from metabolic healthy to unhealthy phenotypes and association with cardiovascular disease risk across BMI categories in 90 257 women (the Nurses' Health Study): 30 year follow-up from a prospective cohort study. Lancet Diabetes Endocrinol, 2018, 6: 714-724
Gulati, M. et al.: 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. In: Circulation, 2021, 144: e368-e454
Marx, N. et al. (Hrsg.) (2023): Klinische Kardiologie – Krankheiten des Herzens, des Kreislaufs und der herznahen Gefäße. 9. Auflage. Springer Verlag, Berlin/Heidelberg, ISBN: 978-3-662-62931-4
Rawahani, A. et al.: Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study. In: Lancet, 2018, 392: 477-486
Saeed, M. et al.: Nine-fold higher risk of acute myocardial infarction in subjects with type 1 diabetes compared to controls in Norway 1973–2017. In: Cardiovasc Diabetol, 2022, 21: 59
Sattar, N. et al.: Age at Diagnosis of Type 2 Diabetes Mellitus and Associations With Cardiovascular and Mortality Risks. In: Circulation, 2019, 139: 2228-2237
Sedaghat, Z. et al.: Association between metabolic syndrome and myocardial infarction among patients with excess body weight: a systematic review and meta-analysis. In: BMC Public Health, 2024, 24: 444
Schütt, K. et al.: Diabetes mellitus und Herz. In: Diabetol Stoffwechs, 2023, 18: S337-S341
Yusuf, S. et al.: Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. In: Lancet, 2004, 364: 937-952
As of: 07.05.2024